Details
Posted: 08-Sep-24
Location: Seattle, Washington
Type: Full-time
Salary: Open
Overview
Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.
With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.
At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.
The Paulovich Lab at Fred Hutch (https://research.fredhutch.org/paulovich/en.html) is an interdisciplinary team whose mission is to develop and implement tools for protein quantification to enable precision medicine via patient selection and characterization of novel therapeutic targets. The lab has a major focus on mass spectrometry (MS)-based proteomics (both untargeted and targeted), as well as integrating proteomic data with genomic data. Our group is highly collaborative, participating in national and international consortia in which teams of scientists, statisticians, and clinicians work together to solve clinical or biological problems to impact human health.
This is a terrific opportunity within the Paulovich lab for a highly motivated and experienced full-time Research Technician III/IV to join our translational proteomics team to help drive translational projects forward towards clinical applications by performing bench-level experiments in support of proteomic, genomic, and transcriptomic analyses of clinical and preclinical biospecimens. The ideal candidate will be able to work as part of a team as well as independently to follow established standard operating protocols (SOP) in a CLIA/CAP laboratory environment.
Responsibilities
Primary responsibilities of RT III/IV:
- Work with antibodies (immunoaffinity purification, immobilization on solid supports, ELISAs)
- Process proteomic samples for LC-MS analysis (e.g., protein extraction, fractionation, immuno-depletion, trypsin digestion, alkylation, reduction, etc.)
- Assist in generation and analysis of mass spectrometry (MS)-based proteomic data
- Follow standard operating protocols (SOP) in a CLIA/CAP laboratory environment including participating in annual competency and proficiency testing
- Collaborate effectively with an interdisciplinary team spanning expertise in medicine, biology, analytical chemistry, and statistics
- Maintain laboratory equipment, records, research results files, and databases
- Assist with written progress reports and development of standard operating protocols (SOPs)
- Assist with writing and co-authoring scientific manuscripts (in peer-reviewed journals)
- Work comfortably in a milestone-driven environment, with quarterly objectives
- Perform other duties as required
Qualifications
MINIMUM QUALIFICATIONS:
Research Technician III:
- Bachelor's degree in a related scientific field or equivalent combination of education and experience
- 5 years of experience working in a lab outside of school coursework (or equivalent combination of advanced degree and work experience)
Research Technician IV:
- Bachelor's degree in a related scientific field or equivalent combination of education and experience
- 8 years of experience working in a lab outside of school coursework (or equivalent combination of advanced degree and work experience)
- Proven ability and knowledge necessary to conduct research independently
PREFERRED QUALIFICATIONS:
Research Technician III:
- 5+ years post degree bench experience in Protein Chemistry, Analytical Chemistry, Clinical Chemistry, Biochemistry, Molecular Biology or related discipline. Salary and title based on experience.
Research Technician IV:
- 8+ years post degree bench experience in Protein Chemistry, Analytical Chemistry, Clinical Chemistry, Biochemistry, Molecular Biology or related discipline. Salary and title based on experience.
Research Technician III and IV:
- Exquisite attention to detail and the ability to adhere to standard operating protocols (SOP) and maintain records.
- Excellent English writing and oral communication skills.
- Proficiency with MS Office programs (Word, Powerpoint, Excel, and Access)
- Ability to multi-task efficiently in a highly interactive, interdisciplinary team environment
- Comfort in a milestone-driven environment, with quarterly objectives
- Willingness to learn new techniques
- Strong work ethic
- Previous experience in a CLIA/CAP or similar clinical lab environment
- Experience with LIMS, database software and proteomics tools
- Previous work with antibodies and peptide standards (immunoaffinity purification, immobilization on solid supports, screening hybridomas for mass spectrometry)
- Previous work in proteomics, genomics, and functional biology
- Previous work maintaining mass spectrometry and HPLC instruments is a plus
- Previous experience with liquid handling robot usage and programming is a plus
- Ability to perform molecular biology and biochemistry experiments on human and animal biospecimens and cell lines is a plus
A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.
Research Technician III: The annual base salary range for this position is from $67,716 to $99,236, and pay offered will be based on experience and qualifications. Research Technician IV: The annual base salary range for this position is from $72,946 to $109,408, and pay offered will be based on experience and qualifications.
This position may be eligible for relocation assistance. Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months).
Our Commitment to Diversity
We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to Human Resources at hrops@fredhutch.org or by calling 206-667-4700.