Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

This position involves working with investigators pursuing the development, and clinical translation, of innovative immunotherapy-based approaches to treat multiple myeloma and other hematologic malignancies. The environment is supportive, team oriented and exciting. The successful applicant will be involved in experiments supporting pre-clinical and clinical projects. The specific assays to be performed include the processing of patient tissue specimens obtained from clinical protocols, validation assays on preclinical and cGMP grade clinical agents (radiolabeled monoclonal antibodies), and mouse models of radioimmunotherapy. There is also the opportunity to apply advanced cellular and molecular biology techniques (e.g., single cell RNA sequencing) to evaluate patient responses after receiving treatment with chimeric antigen receptor T-cell therapy.

Responsibilities

• Performing various mouse specific procedures (including IP, IV, subQ, RO injections; RO bleeding, oral gavage, cardiac puncture and tissue harvest).
• Process patient tissue specimens (blood, bone marrow) for sample storage.
• Coordinate with the clinical team to ensure that patient samples are collected and processed; troubleshoot and address issues as needed.
• Operate a variety of analytical instruments such as gamma counters, dose calibrators, flow cytometers, spectrophotometers.
• Keep detailed records of experiments conducted.
• Prepare and present written or oral progress reports concerning studies including assembly, organization, and interpretation of data.
• Identify methodological problems in research protocols and implement modifications to optimize experimental results.
• Conduct literature reviews to assist in identifying new methods to be used in research.
• Employ cellular and molecular biology techniques including ELISA's, DNA/RNA isolation, sequencing, PCR, RT-PCR, single cell RNA sequencing.
• Perform other laboratory duties as assigned by supervisor.

Qualifications

Minimum Qualifications:

• Bachelor's degree in related scientific field
• Must have experience working with mice and the willingness to develop expertise in how to perform the following mouse procedures: IP, IV, subQ, RO injections; RO bleeds, oral gavage, cardiac puncture, and tissue harvest.
• Superior organization and communication skills
• Prior experience working with mice or wiling to be trained in performance of the mouse specific procedures outlined above
• Comfortable working with small amounts of radiation on a regular basis in a very carefully controlled and monitored setting
• Prior knowledge of Databases
• Research Technician II - at least two years of laboratory experience
• Research Technician III - at least three to five years of laboratory experience

Preferred Qualifications:

• Advanced degree/training
• Extensive flow cytometry experience
• Experience with assay validation and optimization
• Established skills performing Molecular tissue culture, DNA/RNA isolation, sequencing, and molecular analysis
• Previous experience with REDCap
• Experience/familiarity with R and R Studio desired

This position is patient facing and/or requires access to Fred Hutch clinical facilities. As such, full COVID-19 vaccination is required as a condition of employment, without exception. Booster doses are strongly recommended but not required. If declining a booster, completion of the COVID-19 Vaccination Status Form Questionnaire and COVID-19 Booster Declination Training is required. Because of our immunocompromised patient population, there are no medical or religious accommodations available for any employee who is patient facing and/or requires access to Fred Hutch clinical facilities. Only employees whose positions are fully remote, who are not patient facing and/or require no access to clinical facilities, may apply for medical or religious accommodations. As a condition of employment, newly hired employees must provide proof of vaccination before their first day of employment.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The hourly pay range for the II position is from $24.96 to $35.53 and pay offered will be based on experience and qualifications.

The hourly pay range for the III position is from $31.49 to $46.32 and pay offered will be based on experience and qualifications.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months).

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at hrops@fredhutch.org or by calling 206-667-4700.