Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch's global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures for the world's deadliest diseases and make life beyond cancer a reality.
With the Laboratory Director, this role is responsible for the scientific and technical oversight of a clinical/bioanalytical laboratory, which is specialized in Therapeutic Drug Monitoring (TDM). Must ensure compliance with all applicable regulations to ensure high quality testing and patient safety.
Must be able to work independently and collaboratively with the Pharmacokinetics (PK) Laboratory team and upper administration.
Must be accessible to provide oversight of pharmacokinetic modeling of busulfan and subsequent dose recommendations, pharmacogenetics test results and any other active assays.
Ensure that testing systems and methodologies developed and performed for drug concentration analyses meet all quality requirements under CLIA/CAP guidelines.
Ensure that testing reports include necessary information required for attending physicians to choose the optimal dose to attain the desired target exposure as determined by the physician.
Be accessible to the laboratory to provide onsite, telephone, or electronic consultation to laboratory staff and clients during laboratory operating hours.
Evaluate opportunities and lead expansion of billable tests for the Laboratory.
Work with PK Laboratory Director, Manager, and team to optimize existing and new assay methods. Ensure standard operating procedures (SOPs) are written and consistent with the methods performed in the laboratory and are adequate to determine the reliability, accuracy, precision, and other relevant characteristics of test methods. Ensure the establishment and maintenance of acceptable levels of analytical performance per SOP for each testing system and method. Ensure all necessary remedial actions taken are documented whenever significant deviations occur from the laboratory's established performance standards.
Provide consultation to physicians and investigators in developing new treatment plans and clinical research protocols relating to personalized drug dosing and clinical pharmacology. Participate in preparing related publications as primary or contributing author.
Provide opportunities for ongoing education and training for laboratory staff to maintain and enhance expertise in pharmacokinetics and pharmacogenomics testing. Provide education to clinicians and other groups, as appropriate.
Stay up to date with the research and technology and continue to push scientific boundaries in the field of precision medicine.
Earned doctoral degree (PhD) in a chemical, physical, biological or clinical laboratory science or an MD, DO, DPM, DMD, or DCLS degree, at least one year of clinical laboratory experience..
At least 2 years of working experience after terminal degree.
Must be eligible for licensure in the State of Washington.
Must have or be eligible for HHS-approved board certification. Must meet the qualifications as a laboratory director of a laboratory performing high complexity testing under the CLIA '88 regulations, Subpart M, Section 493.1443.
Strong leadership qualities; excellent communication and organizational skills.
Attention to detail; excellent skills in critical thinking, problem solving and ability to make independent decisions.
Demonstrated effectiveness in accomplishing objectives in a complex organization.
Fellowship training and/or post-graduate training is strongly preferred.
Must have board certification.
Prior oncology knowledge/experience.
Experience involving analytical assays for quantitation of drug compounds, such as GC-MSD, LC-MSD, and/or HPLC.
SCCA has a mandatory COVID-19 vaccination policy, and there are no exceptions for any employee who is patient-facing and/or requires access to SCCA facilities.
Exceptions exist only for employees whose positions are fully remote, with no required access to campus. As a condition of employment, newly hired employees requiring access to campus must provide proof of vaccination before their first day of employment.
Our Commitment to Diversity
We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at firstname.lastname@example.org or by calling 206-667-4700.
The Seattle Cancer Care Alliance was incorporated in 1998 as a separate, jointly governed non-profit that included the cancer programs of three partners. Seattle Cancer Care Alliance is a cancer treatment center that unites doctors from Fred Hutchison Cancer Research Center, University of Washington Medical Center, and Seattle Children’s. The purpose of this organization is to provide state-of the-art patient and family centered care; support the conduct of cancer clinical research and education; enhance access to improved cancer interventions; and advance the standard of cancer care regionally and beyond. The Seattle Cancer Care Alliance is the only NCI-designated comprehensive cancer center in the Northwest, and according to the National Cancer Data Base, Seattle Cancer Care Alliance patients in general have better survival rates than patients treated at other cancer treatment centers.