Post Doctoral Research Fellow - Functional Genomics and CryoEM of mRNA Translation
Fred Hutchinson Cancer Research Center
Location: Seattle, Washington
Internal Number: 20244
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutchs pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nations first cancer prevention research program, as well as the clinical coordinating center of the Womens Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employeeswho bringdifferent and innovativeways of seeing the world and solving problems.Fred Hutch is in pursuit of becoming an antiracist organization.Weare committed to ensuring that all candidates hired share our commitment to diversity,antiracism, and inclusion.
This is a joint Postdoc position between the Campbell and Subramaniam labs in the Basic Sciences Division and the Computational Biology Program at the Fred Hutchinson Cancer Research Center in Seattle. The goal of this postdoc project is to combine functional genomic and cryoEM approaches to discover and characterize novel mechanisms of mRNA translation in human cells. Our longer-term goal is to identify how these mechanisms are dysregulated across different tissue types and disease states.
The Campbell and Subramaniam labs are part of the Basic Sciences Division and the Computational Biology Program at Fred Hutch. Lab members come from a variety of scientific backgrounds including physics, biochemistry, and microbiology. Both labs place a strong emphasis on one-on-one mentoring and on providing a supportive environment for learning and research. Trainees are prepared for a wide range of careers in academia and industry through learning of broadly applicable technical and organizational skills. We encourage applicants from historically underrepresented groups and from any disadvantaged socio-economic backgrounds.
The fellow will learn and apply cutting-edge massively parallel assays to identify novel sequence motifs and protein factors regulating mRNA translation in human cells. They will use targeted biochemical and cryoEM techniques to reconstitute and characterize the identified motifs and factors. They will learn and use computational methods to analyze deep sequencing and cryoEM data. The fellow will present their work at group meetings and conferences and write up their work for publication.
The ideal candidate for this project will have PhD-level expertise in applying biochemical or structural approaches to study nucleic acids or proteins.
The applicant will be highly motivated to learn cryoEM and sequencing-based approaches for studying gene regulation.
The candidate should be able to work independently and must have strong communication skills.
To apply, please email the following materials to Melody Campbell (firstname.lastname@example.org) and Rasi Subramaniam (email@example.com): 1. Your CV including contact information for 2 references. 2. A statement of your research interests. This should specifically address why your background and interests are a good fit for this project.
A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.
Our Commitment to Diversity
We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at firstname.lastname@example.org or by calling 206-667-4700.
At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.