Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutchs pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nations first cancer prevention research program, as well as the clinical coordinating center of the Womens Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employeeswho bringdifferent and innovativeways of seeing the world and solving problems.Fred Hutch is in pursuit of becoming an antiracist organization.Weare committed to ensuring that all candidates hired share our commitment to diversity,antiracism, and inclusion.
The Talbot lab is recruiting for a highly motivated and curious Research Technician II or III. Our lab's primary aim is to understand how neuroimmune circuits functional interactions between neurons and immune cells can coordinate immune responses and metabolic functions in the intestine. Using different approaches, our team is providing insights into: how neurons and immune cells communicate in the gut; how microbes and components of the diet can activate gut neurons, affecting intestinal immune-metabolic functions; and how these neuroimmune circuits control gut function, e.g. nutrient absorption. This research is an intersection of different areas (neuroscience, immunology, microbiology, nutrition and gastroenterology) and provides contribution in the understanding of cellular circuits that integrate physiological functions.
One objective of these studies is to develop strategies that use modulation of gut neurons to combat gastrointestinal-associated diseases, as inflammatory bowel disease, irritable bowel syndrome, gut infections with pathogens, malabsorption conditions, and metabolic disturbances.
This is a new lab and the candidate will help the PI setting up the lab, supervise other laboratory personnel and be responsible for the daily operation of the laboratory. The successful candidate will work with the P.I. and other lab members to carry out a variety of cutting-edge pharmacologic, genetic, cellular and molecular techniques in immunology, neuroscience and microbiology, with the aim to uncover neuronal pathways that modulate immune-metabolic functions in the intestine. The Research Technician will directly support the science, contribute to papers, and thrive in an inclusive, supportive, creative, fast-paced and learning-focused environment.
This position works independently under the guidance of, and in conjunction with the Principal Investigator in accomplishing the goals of the laboratory.
This is a new lab and the candidate will help the PI setting up the laboratory, and will be involved with experiments well as as laboratory daily organization.
This position is focused on discovery, supporting research projects, and also involves administrative responsibilities related to lab safety, ordering, and databases. Therefore, it involves be responsible for the daily operation of the laboratory.
It involves performing bench-level experiments that involve: operating and maintaining analytical instruments (e.g. Flow cytometry machine, FACSorting instrument) recovering, compiling and verifying the accuracy of research data; performing calculations, preparing charts, graphs and summaries.
Mice handling (which includes coordination of care for the laboratory mice colony (coordinating breeding, weaning, genotyping).
The candidate will be involved in the following techniques:
Tissue culture of mammalian cell lines and (patient-derived) primary human cells
Flow cytometry-based immunophenotyping, FACS isolation of mammalian cells
Viral vector construction (lentivirus, retrovirus and AAVs), modification, and viral transduction (in vitro and in vivo)
Tissue isolation of immune cells
Immune cell profiling, cytokine production and proliferation assays
Purification, cloning, and manipulation of genomic/plasmid DNA, cDNA, and RNA
PCR and RT-PCR, including Taqman quantitative assays
General laboratory duties and maintenance of laboratory equipment
In vivo experiments in mice models of intestinal inflammation.
Research Technician II Qualifications:
Intermediate level position requiring a minimum of 2 years previous experience working in a laboratory and BA/BS in biological science.
Laboratory research experience including molecular biology techniques is required
Laboratory research experience including cell tissue culture, flow cytometry and mice handling is desired (but not required).
Research Technician III Qualifications:
Advanced position requiring a minimum of 4 years prior experience in a laboratory setting performing experiments with a high degree of independence and a BA/BS in biological science.
Laboratory research experience including molecular biology techniques, cell tissue culture and flow cytometry are required.
Additionally, experience with small animal surgeries and injections is desired (but not required).
Computer skills: Microsoft Excel, Prism (Graphpad), FlowJo, and statistical programs for data analysis.
Excellent organizational and interpersonal skills are required.
Strong troubleshooting skills and the ability to multi-task with precise attention to detail is especially critical.
Experience with infectious murine models, genetically engineered murine models and/or mice handling is desired (but not required).
A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.
Our Commitment to Diversity
We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at email@example.com or by calling 206-667-4700.
At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.