Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutchs pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nations first cancer prevention research program, as well as the clinical coordinating center of the Womens Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
The research technician is responsible for performing standard and investigative laboratory work in support of scientific research by performing bench-level experiments, operating analytical instruments, recovering, compiling and verifying the accuracy of research data; performing calculations; preparing charts, graphs and summaries.
The Program in Immunology in the Clinical Research Division is looking for a highly motivated individual to support the development of genetically modified T cell immunotherapy for cancer. The successful candidate will utilize a variety of cutting-edge cellular and molecular techniques to analyze T cell immunity. The technician will work in the laboratory and be closely involved in the preclinical development of new T cell therapies and their translation into clinical trials. They should be capable of maintaining detailed laboratory records, analyzing data, managing supplies and reporting experimental results in a fast-paced environment.
This position works under the direction of the Principal Investigator and senior laboratory personnel and will be involved in the following techniques/duties:
Tissue culture of mammalian cell lines and (patient-derived) primary human cells
Flow cytometry-based immunophenotyping, FACS isolation of mammalian cells
Lentiviral vector construction, modification, and viral transduction
T-cell cytotoxicity assays, cytokine production and proliferation assays
Purification, cloning, and manipulation of genomic/plasmid DNA, cDNA, and RNA
PCR and RT-PCR, including Taqman quantitative assays
General laboratory duties and maintenance of laboratory equipment
A bachelors degree in a biological science
2+ years of bench research experience
Experience with mammalian cell culture and molecular biology techniques
The candidate must be detail-oriented, a teamplayer and a fast and willing learner. The ideal candidate has prior experience with multicolor flow cytometry, FACS sorting and biological sample handling. Experience working with primary T cells and murine handling are highly desirable.
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At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.