Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutchs pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nations first cancer prevention research program, as well as the clinical coordinating center of the Womens Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
The Immunopathology Lab in the Clinical Research Division is seeking a well-organized and highly motivated Research Technician to join the Multiplex Immunohistochemistry (mIHC) Team with a focus on image acquisition and analysis. The Lab utilizes cutting-edge technologies in a Team Science approach to interrogate the tumor microenvironment through tissue-based analyses of immunotherapy clinical and pre-clinical trials. Determination of Technician II vs III will be based on experience.
Acquire images of brightfield and fluorescence immunohistochemistry, to include 7 or more markers, on a variety of scanning microscopes
Carry out image analyses of brightfield, standard fluorescence, and multiplex immunohistochemistry images including spatial analysis
Work with bioinformatics collaborators to maximize data throughput and interpretation
Act as a digital pathology resource for collaborators
Perform immunohistochemistry and immunofluorescence on automated platforms
Maintain sample and reagent inventories
Make buffers and aliquot reagents
Maintain laboratory records and compile data on experiments and assays in shared databases
Provide methods, images, and data for analysis reports, grant applications, manuscripts, and posters
Participate in weekly lab meetings
BA/BS in biology, immunology, or related field or digital pathology experience (2+ years)
Expertise in image analysis software, such as Definiens or Indica Labs HALO (1+ years)
Must be able to work in a fast-pace environment and multi-task
Detail oriented with good organizational skills
Excellent teamwork with strong written/oral communication skills
Work independently and troubleshoot technical problems
Strong PC computer skills
Microsoft Office proficiency, particularly design and use of spreadsheets
Additional Preferred Experience:
Proficiency with scanning microscopes, such as Leica Aperio or Akoya (PerkinElmer) Vectra systems
Proficiency with immunofluorescence using manual and/or automated platforms
Experience with image management systems such as Indica Labs HALO Link or Leica eSlide Manager
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At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.