Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutchs pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nations first cancer prevention research program, as well as the clinical coordinating center of the Womens Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
A research technician position (full-time) is immediately available in an established laboratory within Fred Hutchinson Cancer Research Centers Translational Research Program. The Laboratory for the Study of Metastatic Microenvironments, directed by Cyrus Ghajar, focuses on understanding the biology underlying disseminated tumor cell (DTC) dormancy and formulating therapeutic means to eradicate dormant DTCs.
We are looking for a dynamic, organized, and highly motivated individual who will be responsible for performing standard and investigative laboratory work in support of research seeking to leverage immunology to target dormant DTCs in order to prevent metastasis. This will entail working with murine models, conducting cell culture experiments, operating analytical instruments, recovering, compiling and verifying the accuracy of research data; and preparing these data as both written and visual summaries.
This position will work under the Principal Investigator and work with the laboratory personnel. The individual will use discretion and judgment in carrying out the following job duties:
Manage a murine colony, including breeding, genotyping, and weaning litters, as well as live imaging and techniques associated with tumor xenograft experiments.
Perform experiments at the bench level to support investigative work. This will involve two- and three-dimensional cell culture, live cell imaging, immunofluorescent staining, tissue sectioning, plasmid preparation, cloning, retro- and lenti-virus production, and immunoblotting.
Prepare and maintain laboratory reagents, stocks, cultures or cell lines.
Learn and conduct cutting edge assays to assess T cell specificity and function.
Perform and modify documented protocols and assays.
Maintain laboratory records and compile data on experiments and assays.
Interpret and report experimental results.
Perform statistical analysis of test results and prepare written reports on work performed.
Operate and carry out basic maintenance of laboratory equipment.
Order and maintain appropriate levels of supplies.
Identify methodological problems in research protocol and implement modifications to optimize experimental results.
Prepare and present written or oral progress reports concerning studies including assembly, organization, and interpretation of data.
Assist in publication of results by proofreading, editing, and contributing ideas.
May perform statistical analyses, write computer programs, or manage research database.
Perform other duties as required.
A bachelors degree in the biological sciences and at least two years experience in basic laboratory skills are required, including experience with murine models and cell culture
Independent research experience outside of laboratory course work is strongly desired, as is a background in tumor biology and/or immunology.
The ideal candidate will be well-organized, pay exquisite attention to detail, have some experience in pre-clinical models, skilled in collecting and analyzing data (e.g., SigmaPlot), and adept in establishing and managing lab databases (Google Sheets, MS Excel).
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At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.