Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutchs pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nations first cancer prevention research program, as well as the clinical coordinating center of the Womens Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
This Research Technician I/II position will work on potentially curative genetic therapies for persistent viral infections. The incumbent will be responsible for performing animal studies to validate the potential of newly developed therapeutics in the lab. Responsibilities will include the production and characterization of in vivo grade therapeutics, performance of animal studies, and the analysis of experimental outcomes in blood and tissues. The technician will work under the direction of the Principal Investigator and senior laboratory members, and work independently using discretion and judgment in carrying out experiments.
The research technician will be required to perform minor murine surgical procedures, including intramuscular, intravenous and intradermal injections, delivery of anesthesia by injection or inhalation, infection with live virus, shaving of fur, blood sampling, and also terminal euthanasia and removal of tissues. Processing of tissue samples for histology and nucleic acid extraction. The technician may be required to assist in the maintenance of a murine colony, which will include breeding and genotyping. Other responsibilities include:
Assisting in the production and purification of viral vector stocks required for animal studies including adeno associated virus, lentivirus and adenovirus.
Work with supervisor and/or senior lab members in the design of experiments, and will be expected to be responsible for the progress of individual research projects, and to analyze data generated and modify techniques.
Identify methodological problems in research protocols and implement modifications to optimize experimental results. Design experiments and develop protocols using techniques including tissue culture, flow cytometry, RNA and DNA extraction, PCR, standard molecular biology methods, tissue sectioning, histology, and immunohisto/cytochemistry.
Prepare and present written and oral progress reports concerning studies including assembly, organization, and interpretation of data.
Conduct literature reviews and background searches to assist in determining research methods.
May perform statistical analyses and manage research database.
Work with supervisor to understand project goals and hypotheses.
Train other members of staff in techniques.
Assist in general maintenance of laboratory including stocking, ordering, maintaining stock and cell lines.
The ideal candidate may work on multiple projects (often simultaneously) so should be highly organized, able to multi-task and have a proven ability to work well with others in a team environment.
Other duties as required.
Research Technician I required qualifications: Bachelor's degree in a related scientific discipline. Basic laboratory skills and scientific knowledge in the area of study and experience with murine models required.
Research Technician II required qualifications: Bachelor's degree in a related scientific discipline. Intermediate level position requiring 2 years previous experience working in a laboratory and working with murine models.
The ideal applicant will have experience with studies performed in small animals including performing minor surgical procedures. Experience with general methods in molecular biology, histology and tissue culture in a quality-conscious, high-throughput environment. Preference will be given to those with experience in virology. A high level of professionalism and respectful communication with animal health staff are required for this position.
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At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.