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The Cooper lab in the Basic Sciences Division at the Fred Hutchinson Cancer Research Center is seeking new postdoctoral fellows. The Cooper lab has a demonstrated history of high impact studies of signal transduction mechanisms associated with mammalian cell migration in cell culture and in vivo model systems.
Potential projects include: investigating the interplay between tyrosine phosphorylation and ubiquitylation in cell migration; the in vivo roles of Cullin 5 ubiquitin ligase complexes; the non-adhesive functions of cadherins in cancer and development; and the dynamics of focal adhesion proteins. We are particularly interested in using live imaging of engineered cells to understand the sequence of events in cellular adhesions. Specifically, we want to know how focal adhesion turnover is regulated differently at the leading edge from under the cell body. What are the signals and how are they relayed to the adhesions? Candidates will be encouraged to build on these ideas and develop new directions for their research projects
Successful applicants will hold a PhD or MD and have extensive experience and interest in cell and/or developmental biology. In addition, applicants should have a 2+ years of experience working on projects in mammalian molecular, cellular or developmental biology. Hands on experience with cell imaging or murine developmental biology is desirable. The candidate should be enthusiastic, scientifically rigorous and inquisitive. Since the Cooper lab is small, the candidate will need the technical skills, confidence and drive it takes to start new directions. The candidate will be responsible for all aspects of their research project. They must be able to function independently and also be highly collaborative. Excellent written and verbal communication skills are essential.
To apply please submit your CV, a cover letter detailing your research interests and suitability for this position, and the names of at least two references.
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At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.