Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
The Stamatatos Lab , within the Vaccine and Infectious Disease Division of the Fred Hutchinson Cancer Research Center, investigates B cell responses to infection and vaccination. Structure- and computer modeling-based approaches are employed to design immunogens and to develop immunization regimens to target and expand specific B cell lineages that are associated with protection from viral pathogens. The activation, survival, and maturation of B cell clonal lineages are monitored by employing complementary immunological, molecular, and cellular techniques and the use of next generation sequencing. Our work encompasses the entire space between pre-clinical and clinical evaluation of candidate vaccines.
We seek outstanding Postdoctoral Fellows interested in studying the activation, proliferation and competition of diverse vaccine-specific B cell clonal lineages in the germinal centers and in developing approaches to guide the maturation of lineages that produce protective antibodies. The work includes studies in transgenic animals and humans.
At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.